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Correspondence
Diving into pooling: an efficient strategy for STI screening in individuals at increased risk
  1. Isabel Aparicio-Calvente1,2,
  2. Silvia Capilla1,2,
  3. Gladys Virginia Guédez-López1,2,
  4. Marta Navarro2,3
  1. 1Department of Microbiology, Clinical Laboratory Service, Consorci Corporació Sanitària Parc Taulí, Sabadell, Spain
  2. 2Institute for Research and Innovation Parc Taulí, Universidad Autónoma de Barcelona, Barcelona, Spain
  3. 3Infectious Diseases Department, Consorci Corporació Sanitària Parc Taulí, Sabadell, Spain
  1. Correspondence to Isabel Aparicio-Calvente; mi.aparicio.calvente{at}gmail.com

https://doi.org/10.1136/sextrans-2025-056518

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    The WHO recommends periodic screening for key sexually transmitted pathogens, such as Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT), in asymptomatic individuals at increased risk of sexually transmitted infection (STI) acquisition. The rise in STIs poses a diagnostic challenge, considering the high costs of molecular techniques and the new recommendations of multisite screening.1 Sample pooling has been proposed for detecting NG, CT and Mycoplasma genitalium (MG), aiming to reduce costs and laboratory workload.2 This study evaluates pooling methodology and compares its performance with conventional individual PCR testing.

    Retrospective samples from …

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    Footnotes

    • Handling editor Anna Maria Geretti

    • Contributors MN provided the study samples. IA-C performed the laboratory testing, with SC and GVG-L supervising these processes. Data analysis and interpretation were conducted by IA-C, SC and GVG-L. All authors contributed to the preparation and revision of the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; internally peer reviewed.