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Correspondence
Proton pump inhibitors (PPIs) and sexually transmissible enteric infections in men who have sex with men: PPI-stewardship
  1. Callum Chessell1,
  2. Deborah Williams2,
  3. Daniel Richardson2,3
  1. 1East Sussex Healthcare NHS Trust, Hastings, England, UK
  2. 2University Hospitals Sussex NHS Foundation Trust, Brighton, UK
  3. 3Brighton and Sussex Medical School, Brighton, UK
  1. Correspondence to Professor Daniel Richardson; daniel.richardson7{at}nhs.net

https://doi.org/10.1136/sextrans-2025-056594

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    Faeco-oral pathogens are sexually transmissible in men who have sex with men (MSM).1 2 Gastric acid suppressants including proton pump inhibitors (PPIs) are used to treat acid reflux and gastric ulcers but can increase the risk of enteric infections.3 PPIs reduce gastric acid secretion, which can increase bacterial survival into the intestine and can alter the composition of intestinal microbiota, affecting microbiota-mediated resistance.3 PPIs are also associated with …

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    Footnotes

    • Contributors DR and CC came up with the correspondence concept. CC drafted the first version. CC, DW and DR contributed to the final manuscript. DR is acting as guarantor.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; internally peer reviewed.